REVIEW: Apathy diagnosis, assessment, and treatment in Alzheimer's disease.
نویسندگان
چکیده
Apathy is defined as a disorder of motivation. There is wide acknowledgement that apathy is an important behavioral syndrome in Alzheimer's disease and in various neuropsychiatric disorders. In light of recent research and the renewed interest in the correlates and impacts of apathy and in its treatments, it is important to develop criteria for apathy that will be widely accepted, have clear operational steps, and be easy to apply in clinical practice and in research settings. Meeting these needs was the focus for a task force that included members of the European Psychiatric Association, the European Alzheimer's Disease Consortium and experts from Europe, Australia and North America.
منابع مشابه
Apathy in Alzheimer's Disease: Any Effective Treatment?
OBJECTIVE This review has evaluated the effectiveness of pharmacological treatment of apathy in patients with Alzheimer's disease (AD). METHODS A systematic literature search was conducted on published clinical trials assessing the effects of pharmacological treatment on apathy in AD over the last 10 years. RESULTS Fourteen studies considered of good quality were included in the analysis (4...
متن کاملApathy Diagnosis, Assessment, and Treatment in Alzheimer’s Disease
doi: 10.1111/j.1755-5949.2009.00132.x Apathy is defined as a disorder of motivation. There is wide acknowledgement that apathy is an important behavioral syndrome in Alzheimer’s disease and in various neuropsychiatric disorders. In light of recent research and the renewed interest in the correlates and impacts of apathy and in its treatments, it is important to develop criteria for apathy that ...
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Introduction:Brain imaging with F-18 fluorodeoxyglucose (18F-FDG) positron emission tomography or Tc-99m hexamethylpropyleneamine oxime (99mTc-HMPAO) SPECT is widely used for the evaluation of Alzheimer's dementia (AD); we aim to assess superiority of one method over the other. Methods: Twenty four patients with clinical diagnosi...
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OBJECTIVE This study examined the effects of modafinil on apathetic symptomatology, performance of activities of daily living (ADLs), and caregiver burden in individuals with Alzheimer's disease (AD). METHOD 23 participants with a diagnosis of mild-to-moderate probable AD according to National Institute of Neurologic and Communicative Disorder and Stroke-Alzheimer's Disease and Related Disord...
متن کاملDysthymia and Apathy: Diagnosis and Treatment
Dysthymia is a depressive mood disorder characterized by chronic and persistent but mild depression. It is often difficult to be distinguished from major depression, specifically in its partially remitted state because "loss of interest" or "apathy" tends to prevail both in dysthymia, and remitted depression. Apathy may also occur in various psychiatric and neurological disorders, including sch...
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عنوان ژورنال:
- CNS neuroscience & therapeutics
دوره 16 5 شماره
صفحات -
تاریخ انتشار 2010